The Upstate SC Alliance, a public/private regional economic development organization, has compiled an annual list of the largest manufacturing employers in the 10-county region of the Upstate. Due to constant fluctuations in employment levels, numbers are typically reported as a range.
The companies on this list produce gas turbines, automobiles and various parts, tires, electrical components, plastic houseware products, frozen foods and vitamin preparations and dietary supplements.
| Company Name | Employee Range | Line of Business |
| BMW | Over 5,000 | Automobile manufacturer |
| Michelin North America | Over 5,000 | Designs, manufactures and sells tires for every type of vehicle |
| Milliken & Company | 2,501-5,000 | Textiles, floor covering, performance materials and specialty chemicals manufacturers |
| GE Power | 2,501-5,000 | Gas turbine manufacturing |
| ZF Transmissions Gray Court LLC | 2,501 to 5,000 | Eight-speed automatic transmission manufacturing, as well as the world’s first nine-speed automatic transmission |
| AFL | 2,501 to 5,000 | Fiber optic cable, transmission and substation accessories, outside plant equipment, connectors, fusion splicers, test equipment and training. |
| DAA Draexlmaier Automotive of America LLC | 1,001-2,500 | Interior parts, e-box, handbrake/gear cover and main harnesses |
| Eaton Corp | 1,001-2,500 | Medium voltage assembly, power distribution, specialty transformer and industrial controls manufacturing |
| Electrolux | 1,001-2,500 | Top-freezer refrigerators and under-the-counter refrigerators |
| Freightliner Custom Chassis Corporation | 1,001-2,500 | Manufactures chassis for RVs, walk-in vans and buses |
| Nestle Prepared Foods Division | 1,001-2,500 | Frozen specialties |
| Robert Bosch LLC | 1,001-2,500 | Gasoline systems and electronic automotive components |
| Sealed Air Corp. | 1,001-2,500 | Plastic bags and film |
| Techtronic Industries Power Equipment | 1,001-2,500 | Power-driven hand tools |
| BorgWarner Inc. | 1,001-2,500 | Powertrain components and transfer cases for the automotive industry |
| Itron | 1,001-2,500 | Electricity meters including smart meters |
| AVX Corp | 501-1,000 | Electronic parts supplier |
| Bosch Rexroth Corp | 501-1,000 | Fluid power pumps and motors |
| Cooper-Standard Automotive | 501-1,000 | PVC automotive trim, molding and seals |
| Carolina Pride Foods Inc | 501-1,000 | Sausages and other prepared meats |
| E&I Engineering Corp. USA | 501-1,000 | Electronic switchgears and busducts |
| First Quality Enterprises Inc. | 501-1,000 | Paper and tissue products, and packaging printing |
| Glen Raven Custom Fabric LLC | 501-1,000 | Performance fabrics for solar protection |
| House of Raeford Farms Inc | 501-1,000 | Poultry and turkey processing |
| Hubbell Lighting Inc. | 501-1,000 | Lighting manufacturers |
| JTEKT/Koyo Bearings North America LLC | 501-1,000 | Nearings, driveline components, steering systems and machine tools primarily for automobile transmissions, torque converters and air conditioning compressors |
| Lockheed Martin Aeronautics | 501-1,000 | Aircraft maintenance, repair, modification & overhaul, Final Checkout & Assembly (FACO) of T-50A and F-16 |
| Lonza | 501-1,000 | Capsule and liquid-filled hard capsules manufacturing, and product development |
| Gestamp | 501-1,000 | Automotive metal stampings and welded assemblies |
| Magna Seating South Carolina | 501-1,000 | Automotive seating manufacturer |
| Mitsubishi Polyester Film Inc. | 501-1,000 | Silicone treated PET films |
| Nutra Manufacturing Inc. | 501-1,000 | Vitamin preparations and dietary supplements |
| Plastic Omnium LLC | 501-1,000 | Automotive components (front end parts of BMWs) |
| Reliable Automatic Sprinkler Company Inc. | 501-1,000 | Fire sprinklers and systems components |
| SAGE Automotive Interiors | 501-1,000 | Automotive textiles |
| Schneider Electric | 501-1,000 | Motor control centers, enclosed drives and starters |
| Siemens Energy Management | 501-1,000 | Electrical apparatus products including panels and lighting |
| Sterilite Corp. | 501-1,000 | Plastic houseware products |
| Tindall Corp. | 501-1,000 | Precast concrete provider |
| Yanfeng Automotive Interiors | 501-1,000 | Automobile interior components including center consoles, door and instrument panels, and seats |
