Day in and day out, logistics providers move merchandise and goods from manufacturers to sales venues throughout the country. Locally, logistics providers serve a variety of industries.
For this list, SC Logistics, an industry cluster supported by the South Carolina Council on Competitiveness, compiled the 15 largest Upstate logistics providers by employee numbers. The organization focused on businesses devoted to logistics functions instead of automotive and tire manufacturers.
| Company Name | Upstate Operations City | Type of business | Number of Employees |
| Walmart | Laurens | Retail logistics provider | 1,300 |
| C&S Wholesale Services | Greenville | Wholesale grocer | 943 |
| Quickway Distribution Services | Anderson | Trucking company | 377 |
| John Cheeseman Trucking Inc. | Greer | Trucking company | 362 |
| Goodwill Industries | Greenville | Nonprofit offering career services, job training, certifications and programs | 342 |
| Southeastern Freight Lines Inc. | Greenville | Trucking company | 300 |
| Columbia Farms | Greenville | Poultry processor | 275 |
| Adidas America | Spartanburg | Distribution for Adidas athletic footwear, clothing and accessories | 250 |
| Dedicated Transportation Solutions | Greenville | Distribution and logistics provider for manufacturers | 220 |
| Tankstar USA Inc. | Spartanburg | Trucking company | 216 |
| Norfolk Southern Railway | Greenville | Railroad company | 180 |
| US Transport Corp. | Greenville | Bulk transportation | 149 |
| C & C Trucking of Duncan | Duncan | Trucking company | 135 |
| Cromer Food Services | Anderson | Vending machine supplier | 122 |
| Beverage South | Greenville | Carbonated soft drinks, bottled and canned beverage industry | 120 |
